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ChE@WSU

Department of Chemical Engineering and Materials Science, Wayne State University

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SNARED:

Membrane fusion is a fundamental life process, necessary for a variety of biological functions, including neurotransimission and the release of hormones.  Triggered by calcium, membrane fusion is regulated by a variety of proteins, the most improtant of which is SNARE.  Recent molecular dynamics simulations provide insight to the mechanism and energetics of the formation of the helical SNARE complex.